Skip main navigation

Military Health System

Hurricane Milton & Hurricane Helene

Emergency procedures are in place in multiple states due to Hurricane Milton & Hurricane Helene. >>Learn More

Corneal Collagen Cross Linking in the Military a Game Changer

Image of Corneal collagen cross-linking, known as CXL, the first and only treatment to date that is proven to stop Keratoconus, KCN, progression. Corneal collagen cross-linking, known as CXL, the first and only treatment to date that is proven to stop Keratoconus, KCN, progression.

For years, Keratoconus has been a disqualifying condition in the military, and a reason why refractive surgery is often denied to service members.

Keratoconus (pronounced Keh·ruh·tow·kow·nuhs), or KCN, is an eye condition where the front part of the eye (cornea) gradually thins out and bulges causing irregularity and blurred vision.

KCN may result from eye rubbing. It has also been linked to sleep apnea, asthma, allergy, eczema, vernal conjunctivitis, floppy eyelid syndrome, connective tissue disorders, or a family history of KCN. Historically, the primary treatment for KCN was contact lenses when eyeglasses were not sufficient to correct the irregular astigmatism. Severe cases were treated with corneal transplantation.

Navy Capt. (Dr.) John Cason, prior ophthalmology specialty leader and refractive surgery advisor, stated that, he reviewed about 2 to 5 sailor applicants per month for possible waiver for accession into the military due to KCN.

In 2016, the Food and Drug Administration approved corneal collagen cross-linking, known as CXL. This is the first and only treatment proven to stop KCN progression.

Air Force Col. (Dr.) Matthew Caldwell, ophthalmology consultant to the Air Force Surgeon General, called CXL a "readiness game changer." He noted that "KCN is of special interest to the military as the age range of impact nearly exactly overlaps years of active-duty service." The onset can happen before or after acceptance into the military when screening is too late.

"KCN impacts the ability to deploy and can degrade vision excluding careers in aviation, Special Forces, and in severe cases, even less visually intensive administrative work," added Caldwell.

Since the FDA approval, hundreds of service members have been treated with CXL. And a majority of these have been able to retain their military careers.

Air Force Col. (Dr.) Joseph Giovannini, cornea specialist at the David-Grant USAF Medical Center at Travis Air Force Base in California stated, "I have seen several military careers saved by the procedure."

Air Force Capt. Lowell DePalma, an aviator who had bilateral CXL, backed up Giovannini, "CXL has allowed me to keep my job and helped my future eye exams to be more predictable."

Currently, ophthalmology consultants are able to recommend acceptance waivers for military candidates with early KCN as long as they are able to show stability after CXL procedure.

"CXL has offered the possibility of military service for a group of candidates with mild symptoms from KCN," stated Cason. In the past, these volunteers didn't have the option of continued service due to restrictive guidelines that did not offer any flexibility with treatment. CXL has given these people the possibility of treatment, stability, and a future military service that were previously denied."

In the future, CXL may also significantly expand the options of vision-enhancing refractive surgery. In the past, service members with abnormal corneal scans were disqualified from refractive surgery. However, over the past decade, CXL plus refractive surgery outcomes have been favorable.

"The advent of CXL has helped tremendously to retain highly trained individuals and increase the applicant pool for the armed services," explained Air Force Lt. Col. (Dr.) James Townley, refractive surgery consultant to the Surgeon General of the Air Force.

As technology continues to advance, the use of CXL and refractive surgery will help more service members remain on active duty.

All authored materials constitute the personal statements of the names listed above and are not intended to constitute an endorsement by the Unites States Air Force or any other Federal Government entity

You also may be interested in...

Report
Jan 1, 2014

MSMR Vol. 21 No. 3 - March 2014

.PDF | 477.89 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Legionellosis in Military Health System beneficiaries, 1998-2013; Urinary tract infections during deployment, active component, U.S. Armed Forces, 2008-2013; Update: heat injuries, active component, U.S. ...

Report
Jan 1, 2014

MSMR Vol. 21 No. 7 - July 2014

.PDF | 634.01 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Sunburn among active component service members, U.S. Armed Forces, 2002-2013; Brief report: sunburn diagnoses while deployed in Southwest/Central Asia, active component, U.S. Armed Forces, 2008-2013; ...

Report
Jan 1, 2014

MSMR Vol. 21 No. 6 - June 2014

.PDF | 526.73 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Brief report: the geographic distribution of incident coccidioidomycosis among active component service members, 2000-2013; Brief report: mid-season influenza vaccine effectiveness estimates for the 2013-2014 ...

Report
Jan 1, 2014

MSMR Vol. 21 No. 8 - August 2014

.PDF | 551.02 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Spread of vaccinia virus through shaving during military training, Joint Base San Antonio-Lackland, TX, June 2014; Gynecologic disorders diagnosed during deployment to Southwest/Central Asia, active component ...

Report
Jan 1, 2014

MSMR Vol. 21 No. 5 - May 2014

.PDF | 531.20 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Numbers and proportions of U.S. military members in treatment for mental disorders over time, active component, January 2000-September 2013; U.S. Armed Forces air crew: incident illness and injury diagnoses ...

Form/Template
Jul 8, 2013

Neuroimaging following TBI in non deployed setting

.PDF | 485.60 KB

The guidance contained in this CR represents a review of currently published literature and expert contributions obtained by the Defense Centers of Excellence for Psychological Health and Traumatic Brain Injury (DCoE) in collaboration with clinical subject matter experts representing the Services, Department of Veterans Affairs (VA), academic, ...

Report
Jan 1, 2013

MSMR Vol. 20 No. 6 - June 2013

.PDF | 528.04 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Incident diagnoses of common symptoms ("sequelae") following traumatic brain injury, active component, U.S. Armed Forces, 2000-2012; Outbreak of Group A beta hemolytic Streptococcus pharyngitis in a Peruvian ...

Report
Jan 1, 2013

MSMR Vol. 20 No. 5 - May 2013

.PDF | 474.96 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Editorial: Can the active component U.S. military achieve tuberculosis elimination?; Tuberculosis trends in the U.S. Armed Forces, active component, 1998-2012; Using the tuberculosis cohort review to evaluate ...

Report
Jan 1, 2013

MSMR Vol. 20 No. 12 - December 2013

.PDF | 548.34 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Bacterial skin infections, active component, U.S. Armed Forces, 2000-2012; Pilonidal cysts, active component, U.S. Armed Forces, 2000-2012; Puumala hantavirus outbreak among U.S. military health care ...

Report
Jan 1, 2013

MSMR Vol. 20 No. 8 - August 2013

.PDF | 584.36 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Septicemia diagnosed during hospitalizations, active component service members, U.S. Armed Forces, 2000-2012; Active surveillance for asymptomatic colonization with multidrug-resistant gram-negative bacilli ...

Report
Jan 1, 2013

MSMR Vol. 20 No. 3 - March 2013

.PDF | 544.63 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Challenges in monitoring and maintaining the health of pilots engaged in telewarfare; External causes of traumatic brain injury, 2000-2011; Mental health diagnoses and counseling among pilots of remotely ...

Report
Jan 1, 2013

MSMR Vol. 20 No. 1 - January 2013

.PDF | 570.93 KB

A monthly publication of the Armed Forces Health Surveillance Branch. This issue of the peer-reviewed journal contains the following articles: Update: Malaria, U.S. Armed Forces, 2012; Confirmed malaria cases among active component U.S. Army personnel, January-September 2012; Editorial: presumptive anti-relapse treatment for malaria in military ...

Skip subpage navigation
Refine your search
Last Updated: July 11, 2023
Follow us on Instagram Follow us on LinkedIn Follow us on Facebook Follow us on X Follow us on YouTube Sign up on GovDelivery