Skip main navigation

Military Health System

Hurricane Milton & Hurricane Helene

Emergency procedures are in place in multiple states due to Hurricane Milton & Hurricane Helene. >>Learn More

Walter Reed Army Institute of Research Implements SARS-CoV-2 Genome Sequencing

Image of Military medical personnel in laboratory. The Walter Reed Army Institute of Research’s Molecular Biology Section processes COVID-19 specimens and collects data. (From left to right: Adam Pollio, Thomas Ryan, Tao Li, Dr. Jennifer Potter-Birriel, and Christine Mariskanish) Credit: Mike Walters, Walter Reed Army Institute of Research

Editor's note: This is the second article in a 7-part series that highlights the work of technicians and scientists in Military Health System laboratories who worked to identify COVID-19 variants using special sequencing technology.

Throughout the last two years, scientists and leaders have worked to identify ways to detect and respond to emerging SARS-CoV-2 variants. The Walter Reed Army Institute of Research'Opens WRAIRs Viral Diseases Branch has played a vital role in these efforts through consistent access to unique samples from various geographic combatant commands. A few of these locations include the U.S. Central Command and U.S. Indo-Pacific Command, as well as multiple recruit and trainee sites within the U.S. Northern Command.

VDB'Ss support for outbreak investigations at these locations has been a valuable asset to the Department of Defense and the Military Health System and provided important force health protectionOpens Health.mil context for controlling SARS-CoV-2 in these DOD high-priority settings.

"The Global Emerging Infections Surveillance and Response System has been a critical partner for the VDB as a sponsor of our SARS-CoV-2 surveillance efforts over the course of the pandemic," said Dr. Matthew Conte, lead of the VDB Viral Genomics and Bioinformatics section. "With their support, we were able to provide near real-time, actionable data that directly informed force health protection measures implemented at DOD installations both at home and abroad."

Military medical personnel at the The Viral Diseases Branch of Walter Reed Army Institute of Research
The Viral Diseases Branch of Walter Reed Army Institute of Research apply advanced next-generation sequencing technologies and bioinformatics analyses to support genomic surveillance of COVID-19 in Military Health System beneficiaries. (From left to right: Adam Pollio, Dr. Jun Hang, Christine Mariskanish, Thomas Ryan, Dr. Jennifer Potter-Birriel, and Tao Li) Credit: Mike Walters, Walter Reed Army Institute of Research

With GEIS support, VDB researchers were also able to develop the Intrahost SARS-CoV-2 K-mer Identification Method, or iSKIM, to rapidly screen genomic datasets and allow early identification of mutations belonging to variants of concern. The iSKIM tool enables the team to quickly prioritize outbreak investigation samples for further downstream analysis. Additionally, iSKIM has been used to scan hundreds of thousands of publicly available raw genomic sequencing datasets to explore the emergence patterns of key SARS-CoV-2 mutations.

"We are proud and excited to be a part of the GEIS'S next-generation sequencing and bioinformatics consortium since its inception in 2017, and we look forward to their continued support of our laboratories in the important endeavor to make genome sequencing an essential part of pandemic preparedness," said Dr. Jun Hang, lead of the VDB Molecular and NGS section

You also may be interested in...

Technical Document
Mar 24, 2020

DOD COVID-19 Practice Management Guide

.PDF | 2.89 MB

This COVID-19 Practice Management Guide has been rapidly and thoughtfully developed by a multi-specialty group of 60 subject matter experts from across the Department of Defense Military Health System. This Practice Management Guideline consolidates resources and optimizes the management of patients requiring clinical care during the global COVID-19 ...

Fact Sheet
Mar 24, 2020

Elective Surgery and Procedures Q & A

.PDF | 42.83 KB

Today, the Department issued guidance directing that all Military Medical Treatment Facilities (MTFs) and Dental Treatment Facilities (DTFs) postpone all elective surgeries, invasive procedures, and dental procedures as of March 31, 2020 for 60 days. This Fact Sheet answers commonly asked questions about that guidance.

Publication
Mar 19, 2020

COVID-19 Life Support Training Extension

.PDF | 361.65 KB

The purpose of this memorandum is to set policy guidance within the Military Health System for American Red Cross life support training (First Aid/cardiopulmonary resuscitation (CPR)/automated external defibrillator (AED), Basic Life Support (BLS), Advanced Life Support (ALS), and Pediatric Advanced Life Support (PALS)).

Congressional Testimony
Mar 11, 2020

Terry M. Rauch, Ph.D., M.P.H., M.B.A. Acting Deputy Assistant Secretary of Defense Force Health Protection and Readiness Regarding U.S. Biodefense and Response to the Novel Coronavirus Outbreak [Testified] Before the House Committee on Oversight and Reform

.PDF | 109.27 KB

Terry M. Rauch, Ph.D., M.P.H., M.B.A. Acting Deputy Assistant Secretary of Defense Force Health Protection and Readiness Regarding U.S. Biodefense and Response to the Novel Coronavirus Outbreak [Testified] Before the House Committee on Oversight and Reform

Publication
Feb 25, 2020

Force Health Protection (Supplement 2) - Department of Defense Guidance for Military Installation Commanders' Risk-Based Measured Responses to the Novel Coronavirus Outbreak

.PDF | 2.06 MB

Novel coronavirus disease (COVID-19) continues to spread and is an increasing force health protection (FHP) threat in areas where Department of Defense (DoD) personnel live and work. As the leading U.S. Government public health agency, the U.S. Centers for Disease Control and Prevention (CDC) continues to assess the risk of COVID-19 and provide ...

Photo
Apr 11, 2018

2018 Medical Support Operations Conference

Acting Assistant Secretary of Defense for Health Affairs Tom McCaffery spoke at the 2018 Medical Support Operations Conference in London, delivering remarks on the defense sector's role in advancing the Global Health Security Agenda. A partnership of more than 60 nations, the Global Health Security Agenda, or GHSA, brings together the unique roles of governments, industry, NGOs, academia, and international institutions to combat infectious disease threats. “We are up against a perilous rise in infectious disease outbreaks threatening the health and safety of our citizens, as well as threatening geopolitical stability,” stated McCaffery, emphasizing that global health security is an essential part of our national security. “The bottom line is that defense and security sectors have a real opportunity to use the GHSA framework to increase collaboration and converge our unique assets across all sectors to detect and defeat disease at the earliest possible moment," McCaffery said.

Acting Assistant Secretary of Defense for Health Affairs Tom McCaffery spoke at the 2018 Medical Support Operations Conference in London, delivering remarks on the defense sector's role in advancing the Global Health Security Agenda. A partnership of more than 60 nations, the Global Health Security Agenda, or GHSA, brings together the unique roles of ...

Photo
Apr 11, 2018

2018 Visit to U.S. Africa Command's Command Surgeon

Acting Assistant Secretary of Defense for Health Affairs Tom McCaffery visits U.S. Africa Command's Command Surgeon and team to discuss the strategic context of global health in advancing shared security objectives with partner nations across the region.  The Department of Defense recognizes that Global Health Engagement activities play a key role to advance U.S. troop operational readiness, build interoperability, and enhance Security Cooperation.

Acting Assistant Secretary of Defense for Health Affairs Tom McCaffery visits U.S. Africa Command's Command Surgeon and team to discuss the strategic context of global health in advancing shared security objectives with partner nations across the region. The Department of Defense recognizes that Global Health Engagement activities play a key role to ...

Publication
Dec 6, 2017

Increasing Partner-Nation Capacity Through Global Health Engagement

.PDF | 196.69 KB

GHE operations, activities, and actions (OAA) are used to implement the Secretary of Defense Policy Guidance for DoD GHE and the U.S. Army Medicine 2017 Campaign Plan in direct support of the U.S. Pacific Command (USPACOM) theater campaign plan (TCP) and U.S. Army Pacific (USARPAC) theater campaign support plan.

Fact Sheet
Aug 30, 2017

Immunization Recommendations for Disaster Response Operations

.PDF | 68.86 KB

This information paper provides immunization recommendations and resources for Department of Defense (DOD) personnel supporting disaster response operations, both in CONUS and OCONUS.

Skip subpage navigation
Refine your search
Last Updated: July 31, 2023
Follow us on Instagram Follow us on LinkedIn Follow us on Facebook Follow us on X Follow us on YouTube Sign up on GovDelivery